These models comprised thirteen clinical known risk factors for CAD, such as age, gender, creatinine, uric acid, cholesterol, LDLC, HDLC, BMI, triglycerides, arterial hypertension, cardiac family history, smoking, diabetes and NT-proBNP [hs-cTnT (β = 1.348; T = 7.046; p = 0.0001), and hs-cTnI (β = 1.643; T = 4.644; p = 0.0001)]. The gene discussed is NPPB; the disease is diabetes mellitus.