Similar to previously published prostate cancer studies [23], recurrent chromosomal abnormalities included losses on chromosomes 10q (including PTEN and MXI1), 12p, 13q (including Rb1), 17p (including TP53), 18q, 6q and 9q (Fig 3, S2 Table). The gene discussed is RB1; the disease is Familial prostate cancer.