Increased levels of soluble endoglin in plasma have been correlated with predicting complications in myocardial infarction [10], acute heart failure [11,12], cardiovascular events in patients with chronic coronary artery disease [13], cardiovascular alterations in patients with hypertension and diabetes, [8] and has diagnostic and prognostic value in preeclampsia [5]. The gene discussed is ENG; the disease is hypertensive disorder.