EHMT2 and breast cancer: BIX-01294 was able to reduce migration (Fig 3A), inhibit anchorage-independent growth (Figs 3B and 6A), increase apoptosis (Fig 6B) and cause cell cycle arrest (Fig 6C), consistent with other independent studies where G9A knockdown also inhibited cell migration and metastasis in breast cancer cells [34] and induced G1 phase cell cycle arrest [50,51].