We collected a panel of 83 patients with surgically resected primary HCC and their matched normal liver tissues from Sir Run Run Shaw Hospital, and performed IHC staining for ADAR1 intratumor and nontumor (NT) expression and scored its immunoreactivities as negative (−), weak positive (+), moderate positive (++) and strong positive (+++) (Figure 4a). This evidence concerns the gene ADAR and hepatocellular carcinoma.