For example, extracts of Hemidesmus indicus and Vanilla planifolia, contain the phenolics 2-hydroxy-4-methoxybenzaldehyde and 4-hydroxy-3-methoxybenzaldehyde which have been shown to demonstrate inhibitory potential against acetylcholinesterase and utility, notwithstanding any toxicity, for treating Alzheimer’s disease and other neurological problems [83] is possible. The gene discussed is ACHE; the disease is early-onset autosomal dominant Alzheimer disease.