Furthermore, there was no statistically significant relationship between HER2 expression with pathological stage (Pearson’s Chi-square = 1.326, P-value = 0.249442, Fisher Exact Test) (Table 6) and the relationship between hormonal status and HER2 with histological type of breast cancer was not statistically significant mostly due very small numbers of lobular, medullary and other non-ductal carcinomas (data not shown). This evidence concerns the gene ERBB2 and breast cancer.