TLR4 and alcoholic hepatitis: In order to determine whether HA35 regulates TLR4-dependent cytokine expression in patients with alcoholic hepatitis (AH), we studied isolated peripheral blood monocytes (PBMCs) from a cohort of patients with moderate to severe AH, with Model for End Stage Liver Disease (MELD) scores ranging from 17–33, as well as a cohort of healthy control subjects.