Interestingly, NUDT4, NUDT5, NUDT6, NUDT7, NUDT8, and NUDT9 were assigned to the same cluster when considering data from the three cancer cell lines together (Fig. 8e, f); however, when examining data collections limited to A549 (Fig. 8g, h) or MCF7 (Fig. 8i, j), these enzymes were assigned to two or three separate clusters, respectively. The gene discussed is NUDT8; the disease is cancer.