Additionally, we also observed that FSCN1 expression is significantly associated with a number of clinical parameters of IDC patients, including tumor size (P = 0.024), grade (P < 0.0001), stage (P = 0.045), ER- (P < 0.0001), PR- (P < 0.0001) and axillary lymph node metastasis (P = 0.024) (Table 2). This evidence concerns the gene ESR1 and neoplasm.