2014). These data were presented in a supplemental figure restricted to survival analysis, which limits the context in which to draw comparisons with our observations (Blanchet et al. 2014). However, the investigators used a different strain of S. aureus and an inoculum more than threefold greater than the highest tested in our studies, suggesting that the contribution of TLR2 to the outcome of staphylococcal pneumonia may depend on the strain and infecting dose of bacteria. Defining the role of TLR2 in pulmonary defense against other isolates of S. aureus will require further investigation. This evidence concerns the gene TLR2 and staphylococcal pneumonia.