TLR2 and staphylococcal pneumonia: Using a murine model of acute staphylococcal pneumonia, we found that the intrapulmonary production of proinflammatory cytokines and chemokines, the recruitment of neutrophils to the lungs, the release of cathelicidin into the airspaces, and bacterial containment by alveolar macrophages all were reduced in TLR2−/− mice in comparison with WT controls.