Our data also reveal that gTAM express higher levels of LIGHT (TNFSF14), a TNF superfamily member that interacts with tumor-associated myeloid cells, NK cells, T cells and tumor cells through its receptors, CD270 and lymphotoxin β, to augment the recruitment, retention and activation of effector cells, resulting in strong antitumor responses (102). The gene discussed is TNFRSF14; the disease is neoplasm.