BRCA1 and prostate carcinoma: Oncogenetic testing of male members of the family is reasonable, not only because they are might be carriers of BRCA mutations and transmit the mutations to their future granddaughters, but also because men who carry the mutated BRCA1 gene have a four times greater chance of developing prostate cancer than other males.36 Knowledge about the mutation status for males may potentially have an impact on the screening and treatment procedures with regard to prostate cancer.