The cytokeratin analysis in individual cells revealed 68% stronger expression of CK18 in prostate cancer cells (n = 16,614) as compared to benign luminal cells (n = 9,576) (0.200 vs. 0.119, p < 0.001), whereas the expression of CK8 was only 14% higher in cancer cells (0.081 vs. 0.071, p < 0.001). This evidence concerns the gene KRT8 and cancer.