Although the mechanisms and the rate of AGR2 secretion from cytoplasm of tumour cells into the blood serum in different cancers might vary considerably47, we speculated that assessing AGR2 expression in tumour tissue along with a blood test for AGR2 protein may potentially lead to a more accurate and comprehensive assessment of the prognostic role of AGR2 in tumours. Here, AGR2 is linked to neoplasm.