Recent studies indicated that numberous lncRNAs such as nuclear paraspeckle assembly transcript 1 (NEAT1), cyclin D2 antisense RNA 1 (CCND2-AS1), taurine-upregulated gene 1 (TUG1) and HOX transcript antisense RNA (HOTAIR) were overexpressed in tumors, and involved in tumor occurrence and progression [26–29]. The gene discussed is HOTAIR; the disease is neoplasm.