For instance, Kouhkan et al. found that cell cycle arrest of glioblastoma multiforme (GBM) cancer cells was induced by miR-192-1's targeting MAPK1. Chen et al. revealed that miR-378 suppressed prostate cancer cell growth through down-regulation of MAPK1 in vitro and in vivo. This evidence concerns the gene MAPK1 and glioblastoma.