IFNG and neoplasm: The decreased tumor growth in mice treated with DFMO and Trimer PTI was associated with a significant increase in the number of IFN-γ producing splenocytes as measured by the ELISpot assay following ex vivo stimulation with SIINFEKL peptide (Figure 3A) as well as an increase in the number of F4/80 positive macrophages in the tumor (Figure 3B).