When the data were stratified for multivariate analysis using the Cox proportional hazards analysis procedures, CTEN immunoreactivity in tumor cells remained significant (P = 0.0423, hazard ratio, 3.5 [1.04–16.4]) for overall survival in all patients, suggesting that CTEN immunoreactivity can be an independent predictor of overall survival. Here, TNS4 is linked to neoplasm.