The apoptotic rate of A549/DDP, A549/PTX and PC9/AB2 cells was indeed elevated by treatment with either anti-cancer drugs (cisplatin, paclitaxel and gefitinib) or (si-SNHG12-1 or si-SNHG12-2), while simultaneous SNHG12 downregulation and drug treatment led to significantly higher apoptotic cells (Figure 3G-3I). Here, SNHG12 is linked to cancer.