Recent studies demonstrated that some biomarkers have been investigated for diagnosing and monitoring sepsis, such as C-reactive protein (CRP) and procalcitonin (PCT), however, these biomarkers levels were also detected to be elevated in patients with many noninfectious conditions, for instance, malignant tumors, acute coronary syndromes, severe trauma, burns, rheumatic disorders, or post-surgery, etc. [4–7]. The gene discussed is CRP; the disease is rheumatic disorder.