In addition to this, due to the correlation between NEO1 and GLI1 expression and to the high variability of GLI1 levels among human BCC samples (Figure 4A), we performed the same analysis on GLI1 mRNA levels and found that they were also significantly lower in aggressive human BCC subtypes compared to non-aggressive subtype samples (Figure 6B). This evidence concerns the gene GLI1 and skin basal cell carcinoma.