However, heparin has also been shown to attenuate P- and L-selectin mediated adhesion of leukocytic cells [34, 60–63], the recruitment of which is indispensable to the maintenance of homeostasis [8, 10, 14] and furthermore has been implicated in preventing the progression of metastasis by engulfing tumor debris and recruiting other cytotoxic cell subtypes [64]. Here, SELL is linked to neoplasm.