In addition to the significantly different expression pattern of miR-199a-5p and HIF-1α in benign and cancerous prostate tissue samples (Tables 1 and 2; Figure 1), the positive rate of HIF-N in PCa with progression (27/58, 46.6%) was significantly higher than that in PCa without progression (15/59, 25.4%, P=0.021; Table 2). The gene discussed is HIF1A; the disease is posterior cortical atrophy.