From the 13 tumor samples in which some phosphorylated ERα could be detected, pS118 appeared much more prominent than either pS294 or pS305; in 7 of these samples (#11, 14, 22, 33, 39, 69, 146), pS294 expression appeared greater than pS305 while in 6 samples (#9, 13, 26, 37, 46, 66) the reverse was apparent. The gene discussed is ESR1; the disease is neoplasm.