After averaging duplicate results and subtracting log2-transformed data for AML-exposed BM-MSC by data for control BM-MSC harvested on the same day, samples for MLL/ENL+FLT3-ITD genotypes (Trp53 wt and Trp53-/-) were nearest neighbors, and also clustered next to the data for MLL/ENL leukemia cells (Figure 1A). The gene discussed is KMT2A; the disease is acute myeloid leukemia.