Dividing the total primary cohort into the different histological subtypes, 44 (70.9%) of the high-grade serous tumors showed BRCA1 promoter hypermethylation, as well as four undifferentiated (66.6%), four clear cell (100%), two mixed (100%), one endometrioid (100%) and one mucinous (100%) tumor sample. This evidence concerns the gene BRCA1 and neoplasm.