Soleus fiber cross-sectional area was smaller in both AS groups than Sham and did not differ between AS-GH and AS (Sham 3,556±447; AS 2,882±422; AS-GH 2,868±591 μm2; p=0.016 AS and AS-GH vs Sham; Figure 1B). The gene discussed is GH1; the disease is aortic stenosis.