When we compared NF1 mRNA expression with different clinicopathological features, we found no significant differences in relation to gender (P=0.141), age (P=0.800), tumor size (P=0.980), lymph-node metastasis (P=0.217), differentiation (P=0.476) and distant metastasis (P=0.416). The gene discussed is NF1; the disease is neoplasm.