Regarding thyroid cancer, Chiappetta et al. recently reported that PATZ1 was downregulated in a large panel of thyroid cancer samples and cell lines, and that restoration of PATZ1 in thyroid cancer cell lines decreased migration, epithelial-mesenchymal transition, and in vivo tumorigenic potential, which demonstrates a tumor suppressor role of PATZ1 in the development of thyroid cancer [20]. Here, PATZ1 is linked to neoplasm.