Notably, Johansson et al. [37] demonstrated that prostate peritumoral mast cells stimulate angiogenesis and tumor growth by secreting FGF2 whereas intratumoral mast cells correlate negatively with the presence of metastases, tumor stage, Gleason score, angiogenesis, and tumor cell proliferation, being associated to a good prognosis. The gene discussed is FGF2; the disease is neoplasm.