PECAM1 and neoplasm: Immunohistochemical analysis was performed on sections of TRAMP-C2 tumor lesions originated in wild type (WT) and TgN(Tie2-hPTX3) mice in order to identify CD31-positive endothelial neovessels (Figure 3A-3D) and the tryptase-positive mast cell infiltrate (Figure 4A-4D) in the central and peripheral areas of tumor grafts.