Mutations in genes other than PIGA, EGFR-AS1, AKT2 and CBLC, were largely distributed in subjects with refractory anemia with excess blasts (RAEB) (n = 56) or the AML with multilineage dysplasia following MDS (MDS-AML) (n = 24). Here, AKT2 is linked to acute myeloid leukemia.