Based on the analysis of the targeted sequencing data of MDS, 17 candidate genes (DNMT3A, GATA1, GATA2, TP53, RUNX1, KRAS, NRAS, SRSF2, TET2, IDH1, IDH2, ETV6, EZH2, BCOR, PTPN11, STAG2, U2AF1) were identified. This evidence concerns the gene EZH2 and myelodysplastic syndrome.