Based on the analysis of the targeted sequencing data of MDS, 17 candidate genes (DNMT3A, GATA1, GATA2, TP53, RUNX1, KRAS, NRAS, SRSF2, TET2, IDH1, IDH2, ETV6, EZH2, BCOR, PTPN11, STAG2, U2AF1) were identified. Here, RUNX1 is linked to myelodysplastic syndrome.