Taking into account of the observed combinations of these phenotypic markers, 394 gastric cancers were classified into 157 intestinal phenotypes (39.8%), 57 gastric phenotypes (14.5%), 124 mixed phenotypes (31.5%), and 56 unclassified mucin phenotypes (14.2%), where PD-L1 positivity was most commonly observed in 56 intestinal phenotypes (45.5%), followed by 40 mixed phenotypes (32.5%), 15 unclassified phenotypes (12.2%), and 12 gastric phenotypes (9.8%). This evidence concerns the gene CD274 and gastric cancer.