However, a recent study has shown that PD-L1 expression was not restricted to gastric cancers with 9p24 amplification [15], which indicates that gastric cancers have multiple mechanisms to induce PD-L1 expression besides 9p24 amplification and suggests that PD-L1/PD-1-driven immune evasion may broadly play an important role in gastric cancers regardless of the prerequisite presence of EBV. Here, CD274 is linked to gastric cancer.