MDM2 and neurodegenerative disease: Survival rate analysis focused on the DNAJ family revealed that decreased survival of mut TP53/high MDM2 breast cancer patients, not only correlated with high expression of DNAJB1, but also with high level of expression of DNAJB6. The latter has been shown to be associated with various diseases and physiological processes, like neurodegenerative diseases, infection diseases, limb-girdle muscular dystrophy, cardiomyocyte hypertrophy and cancer [83].