As shown in Figure 5 and Table 1, nuclear ING5 expression was stronger in breast normal tissue than that in fibroadenoma, adenomatosis and primary cancer (p < 0.05), adenomatosis than primary cancer (p < 0.05), and primary than metastatic cancers (p < 0.05, Table 1). This evidence concerns the gene ING5 and metastatic malignant neoplasm.