Proteins that were less abundant in obese/T2DM muscle but more abundant in exercised muscle include: NADH ubiquinone oxidoreductase subunits A8 (NDUA8), B8 (NDUB8) and S2 (NDUS2); glutamic-oxaloacetic transaminase 2 (AATM) and ATP synthase beta (ATPB). This evidence concerns the gene NDUFA8 and type 2 diabetes mellitus.