There are 3 imprinting genes located on 22q according to www.geneimprint.com/site/genes-by-species.Homo+sapiens: DGCR6L, DGCR6,[23] and FLJ20464.[24] The first 2 genes are related to DiGeorge syndrome, which is frequently associated with congenital heart defects, and that might be the reason for our case. The gene discussed is DGCR6; the disease is 22q11.2 deletion syndrome.