For these analyses, we utilized three microarray datasets that included 240 patient samples representative of the molecular immature (mostly LYL1+), early cortical (mostly TLX1+, TLX3+ or HOXA+), and late cortical (TAL1+) T-ALL disease subtypes (Van Vlierberghe and Ferrando, 2012). The gene discussed is LYL1; the disease is acute lymphoblastic leukemia.