The combined ORs were 2.06 (n = 3 studies, 95% CI: 1.25–3.40, Z = 2.82, P = 0.005) and 2.89 (n = 3 studies, 95% CI: 1.23–6.79, Z = 2.43, P = 0.01) without statistical heterogeneity (I2 = 0% and 17%), indicating that CK-19 expression was associated with larger tumor size. Here, KRT19 is linked to neoplasm.