In this meta-analysis, the relation between the CK-19 expression and overall survival (1-year, 3-year and 5-year) and clinicopathological features, such as tumor size, differentiation grade, vascular and perineural invasion, lymph node and liver metastasis, was studied to assess the impact of CK-19 expression on PNET prognosis. This evidence concerns the gene KRT19 and primitive neuroectodermal tumor.