PDCD1LG2 and Sepsis: In a postmortem study involving sepsis patients, T cell function was shown to be evidently impaired in association with increased expression of PD-1 receptor and activation marker CD69, and a significant decrease in IL-7 receptor and CD28 expression (a co-stimulatory T cell receptor); and increased PD-L1 and PD-L2 expression on dendritic cells [23].