The most prominent proof that the anti-inflammatory and anti-thrombotic effects of fish and marine products (against the PAF-pathway) is mostly attributed at the marine PLs of fish was reported in 2000 by Panayiotou et al. where PLs extracts from fresh and fried cod (Gadus morhua) were found to exhibit potent inhibitory effect towards PAF-induced platelet aggregation, while this effect was related to protective effects of cod against atherosclerosis also through PAF-inhibition [86]. The gene discussed is PCLAF; the disease is atherosclerosis.