CEACAM5 and neoplasm: By univariate analysis, disease-free survival was greater in subjects ≥65 years of age and in those with normal serum carcinoembryonic antigen levels, T1-T2 tumours, absence of blood embolization, absence of lymph node or metastatic invasion, well differentiated tumour histological grade or Primer 2 (ERβ1 and ERβ5) expression levels ≤ −4.5.