MYC and neoplasm: We observed seven let-7 family members (let-7a, let-7b, let-7c, let-7d, let-7e, let-7f, and let-7 g) to be downregulated in eBL tumor cells compared to GC B-cells consistent with their functional role in the genesis and maintenance [29] of eBL tumor cells in the presence of MYC deregulation.