TRIM24 and cancer: Although genomic deletion of mouse TRIM24 promotes hepatocellular carcinoma (HCC)10,11, aberrant overexpression of human TRIM24 is positively correlated with cancer progression and poor survival of patients in multiple cancers, including gastric cancer12, bladder cancer13, non-small cell lung cancer14, human HCC15, head and neck carcinoma16 and breast cancer8,17.