RPTOR and breast cancer: In contrast to what was found for cytoplasmic raptor, high expression of nuclear raptor indicated an improved prognosis for breast cancer patients when the group with low expression was compared with the group with high expression (DMFS HR (medium vs low): 1.06; 95% CI 0.71–1.57; p = 0.78) and (DMFS HR (high vs low): 0.67; 95% CI 0.46–0.99; p = 0.044) (Fig. 4c).