During the first five years after diagnosis, raptor expression in the cytoplasm showed no prognostic value; however, after five years it had a strong prognostic impact with an 89% risk increase compared with patients with low cytoplasmic raptor in the tumor (DMFS HR 1.89; 95% CI 1.18–3.02; p = 0.0078). Here, RPTOR is linked to neoplasm.