CXCL8 and systemic sclerosis: We evaluated the production of CXCL10, CCL4, CXCL8 and IL-6 in circulating classical monocytes, non-classical monocytes and myeloid DCs (mDCs) in patients with diffuse cutaneous (dSSc) and limited cutaneous (lSSc) SSc and compared this to that observed in healthy counterparts (representative dotplots are shown in supplementary Fig. S1).