Recently, Zhang and her colleagues reported that intra-anterior cingulate cortex injection of galanin induced significant increases in HWLs to noxious thermal and mechanical stimulations in rats with neuropathy, the increased HWLs were significantly attenuated by intra-anterior cingulate cortex injection of the GalR 2 antagonist M871, indicating that galanin induces antinociceptive effects in anterior cingulate cortex in rats with neuropathy, and GalR 2 is involved in galanin-induced antinociceptive effects in the anterior cingulate cortex24. The gene discussed is GAL; the disease is neuropathy.