AFP and hepatitis B virus infection: For model 1, the research elements included alpha fetoprotein (AFP) and hepatitis B virus infection status, and the analysis results showed that AFP (HR = 1.423, P = 0.004) was an independent prognostic factor for RFS in patients with cirrhotic HCC; AFP and hepatitis B virus infection status were not prognostic factors for RFS in patients with non-cirrhotic HCC.