PKM and hepatocellular carcinoma: Tumour size (HR = 3.768, P = 0.036), intrahepatic metastasis (HR = 13.071, P = 0.027), TNM stage (HR = 1.255, P = 0.020), vascular invasion (HR = 1.078, P = 0.017) and PKM2 expression (HR = 5.126, P = 0.014) were adverse prognostic factors affecting DSS in non-cirrhotic HCC after resection (Table 3).