Differently, PDGFC (Fig. 3c) is less expressed in microvascular proliferation in comparison to all other GBM regions aside from hyperplastic blood vessel and leading edge, and similarly to PDGFA (Fig. 3a) and PDGFRA (Fig. 3e), it bears a preferential expression in cellular tumour bulk over leading edge. This evidence concerns the gene PDGFRA and glioblastoma.