PDGFA and glioblastoma: As to the age at the time of GBM diagnosis, those with more than 65 years-old are reported to have poorer prognosis12, and among the subjects herein investigated, tumours from patients in this age group are characterised by greater PDGF family expression levels (Fig. 5e) and increased PDGFA expression over PDGFRA (Fig. 5f).