Beads cross-linked with masitinib were incubated with cellular lysates of HMC-1.1 cells (human mast leukaemia), a cell line expressing c-Kit and Lyn (masitinib targets), and HRT18 cells (human colorectal adenocarcinoma), a cell line presenting a gemcitabine sensitisation by masitinib. The gene discussed is KIT; the disease is colorectal adenocarcinoma.